TopoisomeraseTopoisomerase alters the supercoiling of DNA. Topoisomerase cuts the DNA. Topoisomerase type I cuts one strand and topoisomerase type II cuts both strands. Topoisomerase regulates DNA supercoiling. Topoisomerase aids the transcription and replication of DNA. As well as topoisomerase I and topoisomerase II, there is topoisomerase III and topoisomerase IV.
Edited by: Brian P. Chadwickread more ...
Thought-provoking discussions on classic aspects of epigenetics and on the newer, emerging areas.
TopoisomeraseTopoisomerase: Topoisomerase is an enzyme that alters the supercoiling of double-stranded DNA. Topoisomerase acts by transiently cutting one or both strands of the DNA. Topoisomerase type I cuts one strand whereas topoisomerase type II cuts both strands of the DNA. Topoisomerase relaxes the coil and extends the DNA molecule. Topoisomerase helps regulate DNA supercoiling. Topoisomerase aids the transcription and replication of DNA.
As well as topoisomerase I and topoisomerase II, there is topoisomerase III and topoisomerase IV. Topoisomerase III may regulate recombination. Topoisomerase IV regulates the segregation of newly replicated chromosomes.
Molecular Biology ResourcesMolecular Biology Gateway
PCR Information and links on PCR
The Genome Gateway
The Genomics Gateway
The Protocols Gateway
New Molecular Biology Sites
- Flow Cytometry in Microbiology
- Probiotics and Prebiotics
- Corynebacterium glutamicum
- Advanced Vaccine Research Methods for the Decade of Vaccines
- Bacteria-Plant Interactions
- Metagenomics of the Microbial Nitrogen Cycle
- Pathogenic Neisseria
- Human Pathogenic Fungi
- Applied RNAi
- Molecular Diagnostics
- Phage Therapy
- Bioinformatics and Data Analysis in Microbiology
- The Cell Biology of Cyanobacteria
- Pathogenic Escherichia coli
- Campylobacter Ecology and Evolution
- Next-generation Sequencing
- Omics in Soil Science
- Applications of Molecular Microbiological Methods