Caister Academic Press

Genome Analysis

Bacillus: Cellular and Molecular Biology (Third edition)
Edited by: Peter Graumann
Revised, updated and expanded with two new chapters on motility and nucleotide regulation, the third edition of this authoritative reference work provides up-to-date reviews on current Bacillus research.
Analysis of the data generated by genome sequencing, proteomics, and array-based technologies is critically important. Genome analysis answers questions about the function and expression of genes.

Genome Analysis

Sequencing the genome of an organism is only the beginning. Genome analysis is then employed to answer questions about each gene and gene product such as: What is its function? What are the consequences of mutations in the gene? How is it expressed both temporally and spatially throughout the life cycle of the organism? What similar genes exist in other organisms? What literature describes the gene? What genes are involved disease? Model organism databases (MODs) are used to organise this information.

These databases involve many curators who add biological knowledge to the genome sequence, developers who build the hardware and software to hold, query and display this information.

Further reading